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Leadiant Biosciences, Inc., is researching and providing medicines to help people affected by specific rare diseases, including carnitine deficiency, cystinosis, Hodgkin Lymphoma and invasive fungal infections.

Carnitine deficiency

Carnitine deficiency is a metabolic disorder that prevents the body from processing certain fats into energy, particularly during fasting. Primary carnitine deficiency affects males and females in equal numbers and strikes an estimated one in every 142,000 newborns in the United States.1

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Cystinosis is a rare metabolic disease in which an amino acid called cystine accumulates and forms crystals that can damage many organs and tissues, including the eyes and kidneys. Cystinosis affects one in 100,000-200,000 live births in the United States.2

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Hodgkin Lymphoma

Hodgkin Lymphoma is a cancer of the immune system characterized by the presence of a type of cell called the Reed-Sternberg cell. An estimated 9,000 new cases of Hodgkin Lymphoma were diagnosed in the U.S. in 2023.3

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Invasive fungal infections

Invasive fungal infections are those that result when fungi invade and establish themselves within the deep tissues, causing prolonged illnesses often characterized by fever. These infections can involve any part of the body and are common – and especially deadly – in individuals with compromised immune systems.

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1Therrell BL Jr, Lloyd-Puryear MA, et al. Inborn errors of metabolism identified via newborn screening: Ten-year incidence data and costs of nutritional interventions for research agenda planning. Mol Genet Metab. 2014;113(1-2):14-26.

2Dorland’s Online Medical Dictionary. Available at: Accessed on September 28, 2023 (as cited in Glossary: p1).

3Cancer Stat Facts: Hodgkin Lymphoma. National Cancer Institute: Surveillance, Epidemiology, and End Results Program; 2023. Available from: Accessed on September 23, 2023.

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